APT IMAGING OF HEPATOCELLULAR CARCINOMA SIGNALS AN EFFECTIVE THERAPEUTIC RESPONSE IN ADVANCE OF TUMOR SHRINKAGE

APT imaging of hepatocellular carcinoma signals an effective therapeutic response in advance of tumor shrinkage

Aim: The aim of this study was to assess the utility of weighted amide proton transfer (APTw) MRI in three different rodent models of hepatocellular carcinoma (HCC).Methods: APTw MRI was evaluated gift_wrapping in models of diethylnitrosamine (DEN) induced HCC, N1S1 syngeneic orthotopic xenograft and human HepG2 ectopic xenograft.Results: All model

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The past and future of peri-operative interventions to reduce arthrogenic quadriceps muscle inhibition after total knee arthroplasty: A narrative review

Total knee arthroplasty (TKA) improves patient-reported function by alleviating joint pain, however the surgical trauma exacerbates already impaired muscle function, which leads to further muscle weakness and disability after surgery.This early postoperative strength loss indicates a massive neural inhibition and is primarily driven by a deficit in

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